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. 2009 Oct;15(4):244–252. doi: 10.4103/1319-3767.56102

Table 5.

Nature of K-ras Exon1 mutations in colorectal cancer patients from Kashmir valley

Patient ID Age/Sexa Rural/Urbanb Duke's stagec Smoking statusd Node statuse Sitef Typeg Natureh Codon number Base changei Aminoacid change
1X 55/M R A NSk N C AC HNPCC 12 GGT > GAT Gly > Asp
4X 47/F R D Sk P R MAC S 12, 13 GGT > GAT, Gly > Asp
GGC > GAC
8X 51/M U B NSk N C AC S 13 GGC > GAC Gly > Asp
17X 67/F R D Sk P R MAC S 12 GGT > GAT Gly > Asp
23X 71/M R C Sk P R MAC S 12 GGT > GAT Gly > Asp
25X 50/F U B Sk N C AC S 13 GGC > GAC Gly > Asp
30X 44/F R D Sk P C MAC S 12 GGT > GAT Gly > Asp
38X 45/M U D NSk P C MAC S 12 GGT > GAT Gly > Asp
40X 50/M R D NSk P R MAC S 12 GGT > GAT Gly > Asp
44X 61/M R B Sk N C AC S 13 GGC > CGC Gly > Arg
47X 60/F R B Sk N C AC s 13 GGC > TGC Gly > Cys
51X 58/M R C Sk P C MAC s 12 GGT > AGT Gly > Ser
a

Age/Sex: M = Male, F = Female;

b

Rural/Urban: R = Rural, U = Urban;

c

Duke's stage: A -Tumor confined to the intestinal wall; B - Tumor invading through the intestinal wall; C - With lymph node(s) involvement; D - With distant metastasis;

d

Smoking Status: Sk: Smokers; NSk: Nonsmokers;

e

Node Status: N = Negative, P= Positive;

f

Site of tumor: C = Colon, R = Rectum;

g

TumorType: AC = NonmucinousAdenocarcinoma, MAC = MucinousAdenocarcinoma;

h

Nature of tumor: S: Sporadic; HNPCC: Hereditary Nonpolyposis Colorectal Cancer;

i

Base change: Mutated or inserted nucleotide underlined