Table 5.
HLA alleles particularly indicated for coverage of ethnicities in selected equatorial African countries.
| HLA allele | HLA supertype | # of countries | prevalence | score | Cumulative population coverage |
|---|---|---|---|---|---|
| B5802 | B58 | 2 | 10.3 | 20.6 | 12.34 |
| B1503 | B27 | 2 | 7.4 | 14.8 | 22.56 |
| B5301 | B07 | 3 | 4.9 | 14.7 | 31.93 |
| B4901 | Unclassified | 3 | 4.6 | 13.8 | 35.77 |
| B4201 | B07 | 2 | 6 | 12 | 42.23 |
| B4501 | B44 | 3 | 3.8 | 11.4 | 47.41 |
| B1510 | B27 | 2 | 4.25 | 8.5 | 50.57 |
| B1402 | B27 | 2 | 3.95 | 7.9 | 52.84 |
| B3501 | B07 | 3 | 2.2 | 6.6 | 55.8 |
| B8101 | B07 | 2 | 2.6 | 5.2 | 58.49 |
| B5703 | B58 | 2 | 2.5 | 5 | 59.5 |
| B5801 | B58 | 2 | 2.3 | 4.6 | 64.57 |
| A7401 | A03 | 2 | 2.1 | 4.2 | 66.35 |
| B0702 | B07 | 2 | 1.9 | 3.8 | 68.49 |
| B4101 | B44 | 1 | 2.7 | 2.7 | 69.35 |
| A2301 | A24 | 1 | 2.5 | 2.5 | 70.97 |
Table 5 lists allele data for equatorial Africa as obtained from a publicly accessible allele frequency database. Overall frequencies are biased towards HLA-B alleles. ‘Countries’ indicates the number of countries with a substantial sub-population, ‘Prevalence’ gives the median of allele prevalence in available datasets, ‘Score’ provides the product of Countries and Prevalence, ‘Cumulative Population Coverage’ resembles the cumulative average coverage of populations in Kenya, Uganda and Rwanda by adding individual alleles in order of their rank.