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. 2007 Jan-Mar;41(1):16–22. doi: 10.4103/0019-5413.30520

Table 1.

Study designs6

Type of study Description Pros Cons
Case series Subjects with interesting outcomes are presented -Cheap -Selection bias
-Fast -No control group
Cross-sectional Simultaneous assessment of exposure and outcome in a group -Useful in studying prevalence outcomes -No temporal relationship between exposures and
Case-control Subjects selected based on outcome and then exposure is assessed -Overcomes temporal delays-May only require small sample size -Selection and recall bias
-Temporal relationship may not be clear
Cohort Subjects with and without exposure are followed -Feasible when randomization of exposure is not possible -Critically depends on follow-up
-Classification and measurement accuracy
RCT Exposure is randomly determined -Least susceptible to bias -Feasibility
-Generalizability