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. 2010 Nov 15;21(22):3973–3984. doi: 10.1091/mbc.E10-03-0261

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© 2010 by The American Society for Cell Biology

This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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Figure 2. — CNN3 expression in human and mouse placental tissues. (A) Immunohistochemistry of chorionic villi of human placentas at 21 and 37 wk of gestation. CNN3 was detected in the cytotrophoblasts (black arrowheads) and fetal endothelial cells (white arrowheads) but not in the syncytiotrophoblast layer (arrows). (B) Histology of mouse placenta. Transverse sections (4 μm) were stained with hematoxylin/eosin. A few maternal blood sinuses (arrowheads) and fetal blood vessels (arrows) are found within the labyrinth region. Localizations of the labyrinth layer (la), spongiotrophoblast layer (sp), and maternal decidua (d) are indicated. (C) Immunohistochemistry of mouse placental tissues at 8.5 dpc (a, d), 10.5 dpc (b, e), and 12.5 dpc (c, f). CNN3 was detected in the labyrinth layer and maternal deciduas.