Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Nov 15;21(22):3952–3962. doi: 10.1091/mbc.E10-04-0293

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 by The American Society for Cell Biology

This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

PMC Copyright notice

Figure 2. — Expression of NM II-C in embryonic and adult mouse hearts. (A) Immunofluorescence confocal images of an E13.5 mouse heart stained for NMHC II-A (a, green), II-B (b, green), and II-C (c, green) together with desmin (d–f, red), a marker for (cardiac) myocytes. NM II-A is only expressed in nonmyocytes (a, green). Note the lack of colocalization with desmin-positive cardiac myocytes. NM II-B is detected in both myocytes (e, red and green colocalization) and nonmyocytes (e, green) in the heart. NM II-C is detected in myocytes (f, red and green colocalization) but not in nonmyocytes. The bright green spots are autofluorescence from red blood cells in c and f. (B) Immunofluorescence confocal images of adult heart sections from C⁺/C⁺ (a, magnified in b) and C⁻/C⁻ (c, magnified in d) mice. N-Cadherin is a marker for the intercalated disc (red). Nuclei are stained with DAPI (blue). Arrows in b indicates the presence of NMHC II-C (green) in the intercalated disc. NMHC II-C is absent from C⁻/C⁻ intercalated discs (c and d).