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Mercury and arsenite inhibit selenite and lactate transport via Jen1p. Uptake of 1 mM of either selenite (A) or lactate (B) by strain QZ1pJEN1 (black bar) was determined after 30 min in the presence of either 0.2 mM mercuric chloride (Hg2+) or 5 mM sodium arsenite final concentrations. The cells were preincubated with mercury or arsenite for 5 min before initiation of the assay. Strain QZ1 was used as a control (white bar).
