Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Nov 15;21(22):3926–3933. doi: 10.1091/mbc.E10-02-0112

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 by The American Society for Cell Biology

This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

PMC Copyright notice

Figure 1. — Inhibition of STAT1 retards HGF-induced MDCK tubulogenesis. (A) Expression level of STAT1 in control (pPRIME) and STAT1 knockdown lines (18, 19, and 33) was compared by immunoblot with anti-STAT1 antibody. (B) Control cells or STAT1 knockdown cells were grown as cysts and either left untreated (top row) or treated with HGF for 72 h (bottom row). Inhibition of STAT1 blocks the HGF-induced redifferentiation phase. The GFP represents GFP-pPRIME transfectant. Bar, 10 μm. (C) Quantification of tubular structures in the presence of HGF. One hundred GFP-positive structures per sample were counted, and values are the mean ± SEM of three independent experiments. *p < 0.01 and **p < 0.05.