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. 2010 Nov 15;21(22):3926–3933. doi: 10.1091/mbc.E10-02-0112

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© 2010 by The American Society for Cell Biology

This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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Figure 5. — Overexpression of constitutively active form of STAT1 restores redifferentiation of Raf:ER cells in the presence of 4HT. (A) Raf:ER cysts (left) and Raf:ER cysts overexpressing CA-STAT1 were treated with 4HT for 72 h. CA-STAT1 overexpression promotes redifferentiation in activated Raf:ER cysts. Bar, 10 μm. (B) Quantification of cords plus tubules in the presence of 4HT. One hundred GFP-positive structures per sample were counted (mean ± SEM, n = 3). *p < 0.005.