. Author manuscript; available in PMC: 2010 Nov 16.

Published in final edited form as: Toxicol Pathol. 2009;37(7):938–946. doi: 10.1177/0192623309351722

Table 5.

Effect of dietary fat on regional variation in number of polyps in colons of Apc^Min mice.

Site	Number of polyps
	50 μg/kg			100 μg/kg
	B(a)P alone	B(a)P + USF	B(a)P + SF	B(a)P alone	B(a)P + USF	B(a)P + SF
Proximal	3 + 1.0	4 + 0.9	8 + 1.0	2 + 0.5	7 + 0.9	9 + 1.3
Mid	4 + 0.5	6 + 1.0	11 + 2.0	5 + 0.5	10 + 1.5	14 + 2.0^*
Distal	6 + 0.8^*	8 + 1.0^*	14 + 2.0^*	9 + 1.5^*	11 + 1.2^*	18 + 1.7^*

Abbreviations: B(a)P, benzo(a)pyrene; SF, saturated fat; USF, unsaturated fat.

Note: Data from USF were given as representative of B(a)P-alone treatment group inasmuch as their numbers were not much different from the unsaturated group.

P < 0.05 when a comparison was made with the polyp numbers in the proximal region.