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. Author manuscript; available in PMC: 2011 Jun 16.
Published in final edited form as: Neuroscience. 2010 Mar 22;168(1):31–47. doi: 10.1016/j.neuroscience.2010.03.036

Figure 7.

Figure 7

A. RD neuron showing a delay in spike onset with increasing levels of pre-pulse hyperpolarization. B. Under voltage-clamp the same neuron shows a transient outward current that increases at higher levels of hyperpolarization. C. Mean responses of the relationship between spike delay and hyperpolarizing current for 5 RD and 5 RND neurons. D. Delay is reduced in the presence of 4-AP. E. In addition to the effects on delay and the increase in neural spike discharge, 4-AP reduced the after-hyperpolarization following each action potential. a. first action potential shown in D top trace, b. first action potential in D, bottom trace. Note also the increase in the overshoot of the action potential from 13.32 mv (a) to 21.32 mv (b).