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. Author manuscript; available in PMC: 2010 Nov 16.
Published in final edited form as: Am J Psychiatry. 2009 Oct 15;166(12):1375–1383. doi: 10.1176/appi.ajp.2009.08101489

TABLE 3.

Estimates of Exposure Rates, Incident Risk Ratios, Attributable Fractions, and Number Needed to Treat for Highest-Risk Predictors of Incident Major Depression in Elderly Primary Care Patients

Independent Variable Exposure Rate Incident Risk Ratio
Attributable Fraction
Number Needed to Treat
Ratio 95% CI % 95% CI
All study subjects
 Caucasian race 90.11 4.23 0.57 to 31.32 74.06 −67.53 to 95.98 31
 Minor or subsyndromal depression 37.44 2.86 1.33 to 6.15 41.40 11.13 to 61.36 23
 Poor or fair self-rated health 11.67 1.82 0.79 to 4.20 10.91 −4.41 to 23.98 29
 Physical Self-Maintenance Scale total score >0 53.00 2.86 1.19 to 6.84 51.23 9.09 to 73.84 31
 Duke Social Support Index perceived social support subscale score ≤20 44.89 1.73 0.84 to 3.55 25.68 −8.41 to 49.06 48
 Family Emotional Involvement and Criticism total score <7 86.87 3.57 0.83 to 15.35 67.62 −18.44 to 91.15 32
 History of major or minor depression 23.18 2.47 1.12 to 5.44 18.05 0.46 to 32.53 21
 Other psychiatric disordera 12.80 2.67 1.22 to 5.86 17.07 1.41 to 30.24 19
 Total attributable fraction 98.95 85.71 to 99.92

Subjects with minor or subsyndromal depression
 Caucasian race 90.04 2.88 0.37 to 22.01 62.15 −1.31 to 93.80 17
 Poor or fair self-rated health 19.91 1.64 0.61 to 4.39 11.18 −11.09 to 28.99 20
 Physical Self-Maintenance Scale total score >0 65.80 2.22 0.71 to 7.02 44.61 −26.30 to 75.70 22
 Duke Social Support Index perceived social support subscale score ≤20 54.11 1.81 0.71 to 4.60 27.99 −19.92 to 58.87 21
 Family Emotional Involvement and Criticism total score <7 80.09 3.05 0.68 to 13.56 60.79 −36.33 to 88.72 17
 History of major or minor depression 11.69 3.26 1.13 to 9.37 16.50 −0.73 to 30.78 7
 Other psychiatric disordera 17.75 2.34 0.87 to 6.32 16.38 −0.82 to 33.29 12
 Total attributable fraction 96.71 47.86 to 99.79

Subjects with minor or subsyndromal depression and functional disability (Physical Self-Maintenance Scale score >0)
 Caucasian race 94.12 3.05 0.39 to 23.55 63.26 −11.43 to 93.62 14
 Poor or fair self-rated health 29.41 1.46 0.51 to 4.18 9.21 −14.86 to 28.24 27
 Duke Social Support Index perceived social support subscale score ≤20 70.59 1.98 0.69 to 5.73 34.97 −20.57 to 64.93 16
 Family Emotional Involvement and Criticism total score <7 94.12 5.76 0.74 to 44.87 77.78 −36.05 to 96.37 11
 History of major or minor depression 23.53 4.73 1.37 to 16.33 18.56 2.01 to 32.30 5
 Other psychiatric disordera 35.29 3.55 1.18 to 10.68 25.35 1.36 to 43.50 7
 Total attributable fraction 97.54 48.75 to 99.88
a

Data represent a SCID diagnosis of any current alcohol-related or anxiety disorder.