FIG. 2.

Proinflammatory and immunoregulatory cytokines are higher in subjects with detectable gp120. Plasma cytokines were measured by ELISA at baseline and a follow-up time point 6 months later. Subjects with detectable gp120 were compared to subjects without detectable gp120 who were matched by viral load and CD4 count. Each subject is represented by a unique symbol that is consistent throughout all graphs. HIV seronegative individuals were included as a control. The median concentration of TNF-α, IL-6, and IL-10 was higher in subjects with detectable gp120 compared to those without gp120 at baseline and follow-up. Additionally, the concentration of IFN-γ was higher at follow-up.