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. 2010 Oct 28;4:175. doi: 10.3389/fnhum.2010.00175

Table 1.

Significant activations revealed by whole brain (WB) and regions of interest (ROI) analysis.

Contrast Brain structure x y z Zmax score Cluster size P
Emotional vs. neutral Occipital lobe-L (WB) −50 −72 4 4.27 2056 <0.001
Occipital lobe-L (ROI) −50 −72 4 5.98 436 0.021
Caudate body-L (ROI) −16 10 12 3.11 147 0.044
Unpleasant vs. neutral Inferior temporal 52 −54 −20 3.43 818 <0.001
gyrus-R (WB)
Middle occipital −50 −72 4 3.25 3517 <0.001
gyrus-L (WB)
Superior frontal 8 64 16 3.31 9522 <0.001
gyrus, medial-R (WB)
Amygdala-L (ROI) −24 −6 −14 2.82 59 0.022
Amygdala-R (ROI) 22 −6 −16 2.89 46 0.015
Hippocampus-R (ROI) 22 −14 −12 3.28 205 0.040
Neutral vs. unpleasant Ns
Pleasant vs. neutral Middle temporal gyrus-L (WB) −50 −68 2 4.42 775 <0.001
Occipital lobe-L (ROI) −52 −72 2 4.48 350 0.011
Neutral vs. pleasant Ns
Unpleasant vs. pleasant Rolandic operculum-L (WB) −58 6 4 3.68 16887 <0.001
Amygdala-L (ROI) −18 −4 −14 2.65 69 0.036
Amygdala-R (ROI) 24 0 −22 2.73 46 0.025
Pleasant vs. unpleasant Ns

α < 0.001 uncorrected for whole brain analysis (WB) and α < 0.05, corrected for multiple comparisons (family-wise error – FWE) in ROI analyses with a minimum cluster size of k = 5. L, left; R, right hemisphere; ns, no significant activation. The cluster with the largest number of significant voxels within each region is reported. Coordinates x, y, and z of the peak voxels are given in Montreal Neurological Institute space.