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Characteristics of patient populations in included studies
| Characteristic | Studies, n | Weighted mean | Range of study means |
|---|---|---|---|
| Mean age, years | 19 | 55.0 | 47.1–58.0 |
| Female, % | 18 | 80.1 | 63.6–92.0 |
| RF+, % | 13 | 71.4 | 44.0–97.0 |
| Mean disease duration, years | 14 | 11.6 | 8.0–16.6 |
| Mean number of previous DMARDs | 10 | 4.6 | 3.4–5.8 |
| Mean previous biologic duration, months | 10 | 14.9 | 9.0–25.2 |
