Table 2.
Five-Year Survival Rates for Patients With Stage III Disease Stratified by Number of Metastatic Nodes, Primary Tumor Ulceration, and Nodal Tumor Burden
| Primary Tumor Ulceration | Rates by Type and No. of Metastases* |
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of Nodal Micrometastases |
No. of Nodal Macrometastases |
|||||||||||||||||
| 1 |
2-3 |
≥ 4 |
1 |
2-3 |
≥ 4 |
|||||||||||||
| No.† | % | SE | No. | % | SE | No. | % | SE | No. | % | SE | No. | % | SE | No. | % | SE | |
| Absent | 777 | 81.5 | 1.9 | 246 | 73.2 | 3.7 | 46 | 38.0 | 8.5 | 75 | 51.6 | 7.2 | 67 | 46.6 | 7.9 | 50 | 45.4 | 9.1 |
| Present | 531 | 56.6 | 2.9 | 223 | 53.9 | 4.2 | 49 | 34.0 | 8.3 | 88 | 49.4 | 6.2 | 93 | 37.7 | 6.2 | 68 | 29.2 | 6.7 |
NOTE. Stage III disease indicates nodal metastases. Total No. of patients = 2,313.
Abbreviation: SE, standard error.
*
Overall statistical significance, P < .001.
†
Indicates the sample size for each subgroup.