Table 1.
Characteristic | Patients with MAP CRC | Control CRC patients | Total population |
Male, No. (%) | 82 (56) | 124* (46)† | 206 (49) |
Index patient, No. (%) | 113 (77) | 272 | 385 |
Siblings, No. (%) | 34 (23) | 0 | 34 |
Method of detection CRC | |||
Symptomatic, No. (%) | 109 (74) | 272 | 381 |
Surveillance, No. (%) | 34 (23) | 0 | 34 |
Unknown, No. (%) | 4 (3) | 0 | 4 |
Median age (range), y | 54.0 (32.1–81.1) | 52.1 (28.5–79.1) | 53.1 (28.5–81.1) |
Location, No. (%) | |||
Proximal colon | 76 (52) | 107 (39)‡ | 183 (44) |
Distal colon | 21 (14) | 73 (27) | 94 (22) |
Rectum | 38 (26) | 65 (24) | 103 (25) |
Colon, not otherwise specified | 12 (8) | 18 (7) | 30 (7) |
Unknown | 0 (0) | 9 (3) | 9 (2) |
T stage, No. (%) | |||
0 or in situ | 6 (4) | 6 (2) | 12 (3) |
1 | 15 (10) | 33 (12) | 48 (12) |
2 | 22 (15) | 38 (14) | 60 (14) |
3 | 50 (34) | 118 (43) | 168 (40) |
4 | 8 (5) | 18 (7) | 26 (6) |
Unknown | 46 (31) | 59(22) | 105 (25) |
N stage, No. (%) | |||
0 | 85 (58) | 136 (50) | 221 (53) |
1 | 33 (23) | 54 (20) | 87 (21) |
2 | 15 (10) | 29 (10) | 44 (11) |
Unknown | 14 (10) | 53 (20) | 67(16) |
M stage, No. (%) | |||
0 | 125 (85) | 161 (59)§ | 286 (68) |
1 | 12 (8) | 25 (9) | 37 (9) |
Unknown | 10 (7) | 86 (32) | 96 (23) |
Period of diagnosis, No. (%) | |||
1967–1979 | 12 (8) | 20 (7) | 32 (8) |
1980–1989 | 16 (11) | 24 (9) | 40 (10) |
1990–1999 | 69 (47) | 136 (50) | 205 (49) |
2000–2006 | 50 (34) | 92 (34) | 142 (34) |
Country, No. (%) | |||
Germany | 55 (37) | 106 (39) | 161 (38) |
United Kingdom | 42 (29) | 66 (24) | 108 (26) |
the Netherlands | 50 (34) | 100 (37) | 150 (36) |
Unknown for six patients.
P = .046. χ2 test was used. All statistical tests were two-sided.
P = .015.
P < .001.