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. 2010 Nov 16;5(11):e15442. doi: 10.1371/journal.pone.0015442

Figure 1. Comparison of the direct and indirect TR datasets with modifications related to elongation activity.

Figure 1

Comparison of the new nascent TR dataset (this study) with a newly computed indirect TR datasets using the mRNA amount and the mRNA stability [17] that takes into account the effect of the dilution (see discussion), the indirect TR dataset from [9], and mRNA amount with different chromatin related parameters associated with active elongation as H3 trimethylation (H3K36me3, A) or presence of elongation related transcription factors the histone acetyltranferases Esa1p [27] (B) or Gcn5p (C) [25]. To avoid any bias depending on the wideness of the datasets Spearman rank correlation is used. Note that the correlations are always higher for the nascent TR dataset than for the indirect datasets, and that the indirect TR datasets show a better correlation than the mRNA amount data set.