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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Clin Endocrinol (Oxf). 2010 Dec;73(6):798–807. doi: 10.1111/j.1365-2265.2010.03881.x

Table 3.

Pituitary function before and after transsphenoidal surgery.

MAL (n=19) CYS (n=62) BEN (n=25) INF (n=10)
Cases of pituitary disturbances Preexisting Persistent Preexisting Persistent Preexisting Persistent Preexisting Persistent
Hypothyroidism 2 2 6 4 2 2 3 3
Hyperprolactinemia 2 0 16 4 2 0 2 1
Hypogonadism 4 4 6 4 2 2 3 2
Hypocortisolism 2 2 7 6 2 2 3 3
Total 10 8 35 18 8 6 11 9
No. of new cases after TSS (%)
Hypothyroidism 0 0 0 0
Hyperprolactinemia 0 0 0 0
Hypogonadism 1 1 2 0
Hypocortisolism 1 2 2 0
Permanent DI 2 1 0 0
Total of new cases 4 4 4 0
Follow-up (months) 46±33 35±30 67±38^‡ 25±9

Follow-up is expressed as mean ± SD; DI: diabetes insipidus. Data regarding pre-operative hormone replacement were available for every patient.

Impairment of more than one axis was observed in a given patient was as follows:

  • - group MAL (two pts. with two axes altered; one pt. with four axes altered)

  • - group CYS (five pts. with two axes altered; three pts. with three axes altered)

  • - group BEN (two pts. with two axes altered; one pt. with three axes altered)

  • - group INF (one pts. with two axes altered; one pt. with three and one pt. with four axes altered)

^

p<0.05 vs. group INF

‡

p<0.01 vs. group CYS