Table 1.

TM-MIC	MIC2	MIC12	MIC6	MIC8	MIC8.2	AMA1	MIC16
Role in motility and invasion	Motility, Host cell binding	ND	Host cell binding	Rhoptry secretion	CTD complements MIC8	MJ formation, Rhoptry secretion	ND
Trafficking determinant	++ (Di Cristina et al., 2000)	+ (Opitz et al., 2002)	+ (Reiss et al., 2001)	- TS	- TS	- TS	- TS
Binding to aldolase	+ (Buscaglia et al., 2003, Jewett & Sibley, 2003, Heiss et al., 2008)	+ TS	+ TS	- TS	- TS	+ TS	- TS
Substrate for rhomboid cleavage	+ (Opitz et al., 2002, Brossier et al., 2003, Urban & Freeman, 2003, Brossier et al., 2005, Dowse et al., 2005)	+ (Opitz et al., 2002, Brossier et al., 2003, Urban & Freeman, 2003, Brossier et al., 2005, Dowse et al., 2005)	+ (Opitz et al., 2002, Brossier et al., 2003, Urban & Freeman, 2003, Brossier et al., 2005, Dowse et al., 2005)	+ TS	- TS	+ (Howell et al., 2005)	+ TS

TS – this study; ND - not determined.