Relationship between dose of resveratrol and maximal plasma concentration (Cmax) (A) or area under the plasma concentration versus time curve (AUClast) (B) for resveratrol (black, rhombi), resveratrol-4′-O-glucuronide (red, squares), resveratrol-3-O-glucuronide (green, triangles) and resveratrol-3-O-sulfate (blue, crosses) in healthy volunteers, after a dose of resveratrol at either 0.5, 1, 2.5 or 5g ingested on between day 21 and 28 of daily dosing. Values are the mean of 10 volunteers for each dose level. The range of coefficients of variation (as % of the mean) for individual data points is shown in brackets.