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pH modulation by MIBG plus glucose in a rapidly growing human neuroblastoma tumor xenograft. Mice were anesthetized with ketamine and xylazine prior to insertion of a pH electrode into the tumor. Following equilibration, MIBG (32 mg/kg) and glucose (1.5 g/kg) were administered either intraperitoneally (open circle) or intravenously (filled circle) and the intratumoral pH monitored for 1 h
