Skip to main content
. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Cancer Chemother Pharmacol. 2010 Jun 22;67(4):855–865. doi: 10.1007/s00280-010-1388-8

Table 4.

Antitumor activity of BACPTDP in Panc-1 xenografts

# Treatment Dose
(mg/kg)
Maximum body
weight loss (%)
Median T–C Median survival
(days)
TFS Comparison P value
1 BACPTDP 8.0 21 60.0 66.7 ± 7.8 2 1 vs. 4 0.001
2 BACPTDP 6.7 11 34.8 52.7 ± 8.3 0 2 vs. 4 0.009
3 BACPTDP 4.5 6 10.9 27.4 ± 2.0 0 3 vs. 5 0.582
4 CPT-11 60 6 14.3 31.4 ± 1.5 0
5 CPT-11 40 2 9.5 35.0 ± 9.3 0