Table 3.
Odds ratios and 95% confidence intervals of baseline serum 25-hydroxy vitamin D and bladder cancer risk stratified by selected potential effect modifiers, ATBC study
Serum 25-hydroxy Vitamin D (nmol/L) | |||||
---|---|---|---|---|---|
< 50 | ≥ 50 | ||||
Subgroup | # cases/# controls | OR (95% CI) | # cases/# controls | OR (95% CI) | p for interaction |
Season of blood collection | |||||
Darker | 125/115 | 1.40 (0.78 – 2.50) | 25/32 | 1.0 (ref) | |
Sunnier | 73/56 | 2.28 (1.27 – 4.11) | 27/47 | 1.0 (ref) | 0.24 |
Physically active | |||||
No | 158/140 | 1.65 (1.05 – 2.60) | 45/65 | 1.0 (ref) | |
Yes | 40/31 | 2.62 (0.94 – 7.30) | 7/14 | 1.0 (ref) | 0.41 |
α-Tocopherol supplementation | |||||
No | 106/72 | 2.36 (1.34 – 4.18) | 27/43 | 1.0 (ref) | |
Yes | 92/99 | 1.35 (0.75 – 2.46) | 25/36 | 1.0 (ref) | 0.18 |
Time from blood collection to case diagnosis | |||||
< 10 years | 96/89 | 2.59 (1.38 – 4.85) | 33/40 | 1.0 (ref) | |
≥10 years | 102/82 | 1.33 (0.77 – 2.30) | 19/39 | 1.0 (ref) | 0.11 |
Unconditional models adjusted for matching factors (age and date of baseline blood draw).