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. Author manuscript; available in PMC: 2011 Nov 5.
Published in final edited form as: Org Lett. 2010 Nov 5;12(21):4952–4955. doi: 10.1021/ol102087r

Table 4.

N-Sulfonyl Triazole Synthesis: Scope with Respect to Copper(I) Carboxylate

graphic file with name nihms-244110-t0030.jpg

entry CuOR ratio 7:8a (PhCCH consumed (%a))
toluene water
1 CuTC >100:1 (98)b,c >100:1 (95)b,c
2 CuOAc >100:1 (40) 26:1 (88)b
3 CuOTf >100:1 (17) 5:1 (27)
4 CuFCd >100:1 (>99) 31:1 (93)b
5 CuOAce >100:1 (55) 13:1 (32)
a

As determined by LC/MS, see Supporting Information for details.

b

TsN3 undetected by LC/MS.

c

2 h.

d

CuFC = copper(I)-furan-2-carboxylate.

e

With the addition of thiophene (10 mol %).