Table 6.
Numbers of offspring with and without schizophrenia, relative risks (RR) and 95% confidence intervals (CI) and effects of additional adjustment for SES, by paternal and maternal education
| Schizophrenia |
Crude RR | 95% CI | RRa | 95% CI | RRb | 95% CI | P-value | ||
|---|---|---|---|---|---|---|---|---|---|
| − | + | ||||||||
| Paternal education (years)* | |||||||||
| 13+ | 26,905 | 168 | 1 | 1 | 1 | ||||
| 9–12 | 30,367 | 206 | 1.0 | 0.8–1.2 | 1.0 | 0.8–1.3 | 1.0 | 0.8–1.2 | 0.9 |
| 5–8 | 19,373 | 166 | 1.2 | 1.0–1.5 | 1.2 | 1.0–1.6 | 1.1 | 0.9–1.4 | 0.4 |
| 0–4 | 5,153 | 45 | 1.2 | 0.8–1.6 | 1.1 | 0.8–1.6 | 0.9 | 0.6–1.4 | 0.7 |
| Unknown | 6,394 | 52 | 1.1 | 0.8–1.4 | 1.1 | 0.8–1.5 | 1.0 | 0.7–1.3 | 0.8 |
| Maternal education (years)** | |||||||||
| 13+ | 22,750 | 150 | 1 | 1 | 1 | ||||
| 9–12 | 29,854 | 181 | 0.9 | 0.7–1.1 | 0.9 | 0.7–1.2 | 0.9 | 0.7–1.1 | 0.4 |
| 5–8 | 21,416 | 180 | 1.2 | 0.9–1.4 | 1.2 | 1.0–1.5 | 1.1 | 0.9–1.4 | 0.3 |
| 0–4 | 8,245 | 74 | 1.1 | 0.9–1.5 | 1.2 | 0.8–1.6 | 1.0 | 0.7–1.4 | 0.9 |
| Unknown | 5,927 | 52 | 1.1 | 0.8–1.5 | 1.1 | 0.8–1.5 | 1.0 | 0.7–1.4 | 1 |
a
Adjusted for sex, paternal and maternal age, duration of marriage, and birth order
b
Additionally adjusted for paternal social class