. Author manuscript; available in PMC: 2010 Nov 17.

Published in final edited form as: Cancer. 2006 Dec 1;107(11):2559–2566. doi: 10.1002/cncr.22321

Table 2.

Overall sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of FNA for a histopathological diagnosis of thyroid cancer according to two treatments for a cytological interpretation of follicular neoplasm*. Ukrainian-American Cohort Study of Thyroid Cancer and Other Thyroid Diseases (1998-2000).

	Cytological interpretation
	PTC+Suspect PTC+FN^¶	PTC+Suspect PTC^†
Sensitivity	100% (44/44)^**	77.3% (34/44)
Specificity	17.6% (6/34)	97.1% (33/34)
PPV	61.1% (44/72)	97.1% (34/35)
NPV	100% (6/6)	76.7% (33/43)

Sensitivity TP/ (TP + FN)

Specificity TN/ (TN+ FP)

PPV TP/ (TP+FP)

NPV TN/ (TN+FN)

* Histopathology is considered positive if diagnosis is PTC or FTC, otherwise it is considered negative.

^¶

Cytology is considered positive if FNA interpretation is PTC, suspect PTC, or FN, otherwise it is considered negative

^†

Cytology is considered positive if FNA interpretation is PTC or suspect PTC, otherwise it is considered negative.

^**

From Table 1