Fig. 4.

Phylogenetic reconstruction of the MenB strains used in this study. MLST-based phylogenetic reconstruction is shown of the 124 strains that were MATS typed in this study. Color coding shows antigens at or above the PBT. Strains killed in the SBA with postimmune serum from adult vaccinees are coded by a thick black border. Major clonal complexes (CC) are indicated with the founder CC. The phylogenetic tree was obtained with the Neighbor program from the PHYLIP package, with branch lengths computed from the Kimura two-parameter distances.