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Uterine epithelial-specific E2-regulated responses. Ltf expression by using real-time PCR analysis (A), IHC analysis of lactoferrin (B), and progesterone receptor (C) protein expression in WT (Left) and UtEpiαERKO (Right) uteri when treated with vehicle, E2 or E2 + ICI for three consecutive days (n = 7). (Scale bar: 40 μm.) Arrowheads indicate the positive staining of lactoferrin. Results are mean ± SEM. ***p < 0.001, significantly different from vehicle of the corresponding genotype.
