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. 2010 Jul 14;9(11):2369–2390. doi: 10.1074/mcp.M110.001370

Fig. 10.

Fig. 10.

A, sequence alignment of precursors of V. eremius goannatyrotoxin (GU441529) (1), the frog skin antimicrobial peptide P80952 from Phyllomedusa bicolor (2), and the related non-toxin, ordinary body peptides from H. sapiens (P10082) (3), Anguilla japonica (Q76CL2) (4), and Gallus gallus (P28673) (5). A box indicates a post-translationally processed bioactive peptide. The second Y with a black background is in amide form. * designates the N and C termini of a post-translationally processed peptide sequence. B and C, effect of intravenous injection of V. eremius goannatyrotoxin (GU441529). P1, phase 1; P2, phase 2; P3, phase 3; MAP, mean arterial pressure.