Fig. 5.

Merged network pathway analysis of proteins involved in cellular assembly and organization, cellular compromise, and protein folding that were identified in cytoplasmic fraction. Proteins shaded in green indicate a 2-fold or greater decrease in abundance, and proteins shaded in red correspond to a 2-fold or greater increase in the cytoplasmic fraction of HRSV-infected cells. The color intensity denotes the degree of abundance. Proteins in white are those identified through the Ingenuity Pathways Knowledge Base. The shapes denote the molecular class of the protein. A solid line indicates a direct interaction, and a dashed line indicates an indirect interaction. The yellow lines denote the linkage between the pathways through NF-κB and STAT1 signaling. A full explanation of lines and relationships is provided in supplemental Fig. 3.