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. 2008 Jul 4;1:2.

Table 3:

Results of separate Cox’s models predicting relative hazard of early or late lost to follow-up and death after HAART initiation in the PART initiative, Yaoundé and Douala, Cameroon, (March 2003– January 2005)

Death First 6 months
Death After 6 months
Loss to follow-up Death or lost to follow-up a Loss to follow-up Death or lost to follow-up a
Variable

CD4 counts
≥50 1.0 1.0 1.0 1.0 1.0 1.0
< 50 1.8 (0.3–10.7) 2.3 (1.4–3.7) b 2.3 (1.5–3.7) b 1.4 (0.1–16.3) 1.0 (0.4–2.0) 1.0 (0.5–2.1)
Active TB
No 1.0 1.0 1.0 1.0 1.0 1.0
Yes .... 1.8 (1–3.6) b 1.6 (0.8–3.2) ..... 2.2 (0.8–6.5) 1.9 (0.7–5.6)

Note. Data are adjusted hazard ratio (95% CI). Hazard ratios were estimated for the time-to-event outcomes of death, lost to follow-up and death or lost to follow-up using an extended Cox model allowing for a time-dependent variable (SAS PHREG Procedure). We defined for each variable in the model, a product term with a heavy side function of time (before and after 6 month) based on the pattern of the survival curves. Analyses were adjusted on site, WHO stage, previous HAART. TB, tuberculosis.

a

We performed sensitivity analysis to estimate to hazard of death in a worst-case scenario where we considered all the losses to follow-up as deaths.

b

Significant hazard ratio at 5% level of significance.