Figure 8.

Space time diagram of cell state as a function of position (horizontal axis) and time (vertical axis) in a uniformly proliferating tissue with a linear growth rate. Due to proliferation throughout the tissue, the length increases with time t as L(t) = t + 2. The parameters in the Jaeger and Goodwin model [50,51] are set as A = 0.5, B = 5, T₀ = 1 for 0 <t < 50. The cell state ranges from -10 <z < 10 and this is represented on the graph as shading between black and white (corresponding to z = -10, z = 10 respectively). The region above the dotted yellow line has segmented. Areas outside the tissue are coloured in blue.