Table 3. Competing risk proportional hazard regression analyses of time to therapeutic progression.
Addition of an antidiabetic medicine or switch to insulin | Addition of an antidiabetic medicine or switch to any antidiabetic medicine | |||||||||||
SHR | 95% CI | P value | SHR | 95% CI | P value | |||||||
Number of unrelated comorbidities | 0.872 | 0.839–0.905 | <0.001 | 0.879 | 0.852–0.907 | <0.001 | ||||||
Cancer | 0.703 | 0.590–0.836 | <0.001 | 0.690 | 0.605–0.788 | <0.001 | ||||||
Chronic obstructive pulmonary disease | 0.866 | 0.778–0.963 | 0.008 | 0.855 | 0.786–0.930 | <0.001 | ||||||
Dementia | 0.682 | 0.519–0.895 | 0.006 | 0.636 | 0.512–0.791 | <0.001 | ||||||
Depression | 0.803 | 0.742–0.868 | <0.001 | 0.781 | 0.734–0.832 | <0.001 | ||||||
Urinary incontinence | 0.794 | 0.542–1.164 | 0.237 | 0.752 | 0.555–1.02 | 0.067 | ||||||
Parkinson's disease | 0.565 | 0.457–0.698 | <0.001 | 0.635 | 0.544–0.742 | <0.001 | ||||||
Age | 0.975 | 0.972–0.977 | <0.001 | 0.981 | 0.978–0.983 | <0.001 | ||||||
Number of hospitalisations | 0.776 | 0.744–0.809 | <0.001 | 0.811 | 0.788–0.834 | <0.001 | ||||||
Adherence to antidiabetic medicines | 0.599 | 0.556–0.644 | <0.001 | 0.545 | 0.513–0.579 | <0.001 | ||||||
Residency (aged care versus community) | 0.892 | 0.853–0.934 | <0.001 | 0.884 | 0.849–0.920 | <0.001 | ||||||
Endocrinology service | 1.196 | 1.145–1.250 | <0.001 | 1.317 | 1.269–1.367 | <0.001 |
SHR, Subdistribution Hazard Ratio from multivariable competing risk regression analyses.