Figure 1.
Colocalization of tyrosine hydroxylase and alpha-synuclein or GFP in the substantia nigra. Immunofluorescent staining of tyrosine hydroxylase (A, E), GFP (B), and human alpha-synuclein (F) 3 weeks following AAV1/2 injections. Panels C and G represent merged images of A + B and E + F, respectively. Panels D and H represent high power confocal images revealing aggregates of human alpha-synuclein and GFP within a TH neuron of the substantia nigra and confirmed by the orthogonal view of each panel. Scale bar is 500 μm.