Table 2.

Stroke scoring

Grade	Score	Criteria
Normal	0	No observable deficit.
Mild	1	Slight reduction of activities or mild excitation.
	2	Significant reduction of activities or hyperirritability.
Severe	3	Unable to walk, decreased responsiveness.
	4	Unable to stand, limb paralysis, or paralysis of one side of the body.

The severity of stroke in stroke prone spontaneously hypertensive rats (SHRsp) was assessed with the neurologic examination grading system of stroke as previously reported [26]. When the score was 1 or 2, the severity of stroke was mild, and when the score was 3 or 4, the severity was severe.