Table 3. Two-marker haplotype association results for most significant SNPs in CFI region.
| SNPs | Haplotype | Frequency of affected (%) | Frequency of unaffected (%) | Degrees of freedom | CHISQ | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|
| rs13117504∣rs10033900 | OMNIBUS | NA | NA | 3 | 34.61 | 1.48E−07 | NA |
| rs13117504∣rs10033900 | CT | 50.07 | 40.92 | 1 | 32.52 | 1.18E−08 | 1.448 |
| rs13117504∣rs10033900 | GC | 33.64 | 41.48 | 1 | 25.51 | 4.39E−07 | 0.715 |
| rs13117504∣rs10033900 | CC | 12.39 | 13.25 | 1 | 0.6447 | 0.4220 | 0.926 |
| rs13117504∣rs10033900 | GT | 3.90 | 4.35 | 1 | 0.5068 | 0.4765 | 0.891 |
Abbreviations: CHISQ, χ2-value; NA, Not Applicable (OMNIBUS is a test of all haplotypes)17; SNPs, single nucleotide polymorphisms tested as haplotypes.