Table 1. Single SNP FBAT for association of 6 Tag SNPs in the DLX1/DLX2 genes in MPX families with ASD.
Sample 1 MPX (N=138) | Sample 2 MPX (N=169) | Combined MPX (N=307) | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Allele | S | E(S) | Z | P | Pcor | S | E(S) | Z | P | Pcor | S | E(S) | Z | P | Pcor |
rs788172 | A | 139 | 152 | −1.617 | 0.11 | 101 | 121 | −2.814 | 0.0049 | 0.039 | 240 | 273 | −3.095 | 0.002 | 0.016 | |
G | 247 | 235 | 1.617 | 223 | 203 | 2.814 | 470 | 438 | 3.095 | |||||||
rs788173 | A | 135 | 145 | −1.256 | 0.21 | 89 | 118 | −4.108 | 0.00004 | 0.0003 | 224 | 263 | −3.72 | 0.0002 | 0.0016 | |
G | 239 | 230 | 1.256 | 229 | 200 | 4.108 | 468 | 430 | 3.72 | |||||||
rs813720 | C | 141 | 155 | −1.725 | 0.085 | 107 | 133 | −3.4 | 0.0007 | 0.0054 | 249 | 288 | −3.548 | 0.0004 | 0.0031 | |
G | 245 | 232 | 1.725 | 249 | 224 | 3.4 | 495 | 457 | 3.548 | |||||||
rs13390848 | T | 106 | 103 | 0.494 | 0.62 | 116 | 100 | 2.388 | 0.017 | 0.14 | 222 | 202 | 2.02 | 0.043 | ||
G | 218 | 222 | −0.494 | 190 | 207 | −2.388 | 408 | 428 | −2.02 | |||||||
rs4519482 | A | 97 | 123 | −3.441 | 0.0006 | 0.0046 | 84 | 98 | −2.123 | 0.034 | 181 | 221 | −3.982 | 0.00007 | 0.0005 | |
T | 217 | 192 | 3.441 | 166 | 152 | 2.123 | 383 | 344 | 3.982 | |||||||
rs743605 | A | 139 | 159 | −2.5 | 0.012 | 0.096 | 171 | 181 | −1.24 | 0.21 | 310 | 340 | −2.641 | 0.0083 | 0.066 | |
G | 213 | 193 | 2.5 | 231 | 221 | 1.24 | 444 | 414 | 2.641 |
Pcor: Corrected P-values. See Methods for a description of the correction applied for multiple testing.