Table 1. Immunological characteristics of three dine SCID patients.
Test (normal values) | Patient 1 | Patient 2 | Patient 3 |
---|---|---|---|
ALC (3.7–9.6 × 109/l) | 0.66 | 0.06 | 0.46 |
CD3 (53–84%) | <1% | 2% | 2% |
CD4 (27–56%) | N/D | <1% | 1% |
CD8 (11–37%) | N/D | <1% | 3% |
CD19 (6–24%) | N/D | 3.7% | 2% |
CD16 (8–23%) | N/D | N/D | 57% |
IgG (176–601 mg/dl) | 114 | 1170 | 196 |
IgA (3–73 mg/dl) | <17 | 11 | 11 |
IgM (17–105 mg/dl) | <15 | <6 | 15 |
PHA (65 189±651 c.p.m.) | 0 | 176±1.4 | 0 |
Con A (17 745±177 c.p.m.) | N/D | 617±5.0 | N/D |
PWM (15 578±109 c.p.m.) | N/D | 1910±9.5 | N/D |
N/D, not done; ALC, absolute lymphocyte count at diagnosis.