Table 1. Estimation of the difference in frequencies of alleles in OPTB haplotype in patients' chromosomes (D) and control relatives' chromosomes not transmitted to the patients (C).

Marker locus	Allele	D, % n=16	C, % n=15	P-valuea
CA repeat in AC034259	4	100	26	<0.0001
dbSNP884826:A>G	A	100	40	0.0002
dbSNP2075609:A>G	A	100	80	0.1012
D11S987	5	100	33	<0.0001

^aFisher's exact probability test.