Table 2. Linkage disequilibrium analysis between OPTB locus in Chuvashians and microsatellites closed to the TCIRG1 gene.

Marker	Allele	P-value	χ2	δ±95% CI	g	g0	g+g0
D11S4076	1	0.2435	01.36	0.242±0.385
D11S1883	2	<0.0001	27.03	0.778±0.200	10.18	9.35	19.53
D11S913	2	<0.0001	23.90	0.943±0.111
D11S1889	2	<0.0001	36.35	0.954±0.088
TCIRG1	mut
D11S987	5	<0.0001	21.35	0.939±0.119
D11S4113	12	<0.0001	46.14	0.850±0.159	30.45	16.05	46.50
D11S4136	4	0.0353	04.43	0.282±0.272	30.08	7.02	37.10
D11S4139	6	0.0089	06.84	0.320±0.254	20.76	5.88	26.64
D11S4207	15	0.1202a		0.117±0.174
				32.4±11.8b

^aP-value, Fisher's exact probability one-tailed test.

^bMean age in generations and standard deviation.

δ, the degree of linkage disequilibrium by Bengtsson and Thomson¹⁹; g, by Risch et al²¹; g₀, by Labuda et al.²²

Estimating the age of the 807+5G>A mutation in TCIRG1 gene in Chuvashians.