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. 2008 Nov 26;17(5):620–628. doi: 10.1038/ejhg.2008.202

Table 3. Association of genotypes with the expression of type III HLP.

  Type III HLP, N (%) Normo, N (%) OR (95% CI) P-value
APOC3 3238 G>C
 1/1 78 (69.6) 44 (86.3) 2.7 (1.1–6.7) 0.03
 1/2+2/2 34 (30.4) 7 (13.7)    
         
APOA5 −1131 T>C
 1/1 75 (70.8) 45 (88.2) 3.1 (1.2–8.0) 0.02
 1/2+2/2 31 (29.2) 6 (11.8)    
         
APOA5 c.56 G>C
 1/1 84 (79.2) 46 (90.2) 2.4 (0.9–6.7) 0.12
 1/2+2/2 22 (20.8) 5 (9.8)    
         
LPL c.27 G>A
 1/1 100 (88.5) 51 (98.1) 6.6 (0.8–52.1) 0.07
 1/2+2/2 13 (11.5) 1 (1.9)    
         
Cumulative ¥
 Non-carrier 48 (42.5) 38 (73.1) 3.7 (1.8–7.5) <0.0001
 Carrier 65 (57.5) 14 (26.9)    

Type III HLP: type III hyperlipidemic patients; normo: normolipidemic E2/2 subjects; OR: odds ratio; 95% CI: 95% confidence interval; 1/1, homozygous for the common allele; 1/2 heterozygous for the common and rare allele; 2/2, homozygous for the rare allele; cumulative ¥: non-carrier represents non-carrier of the rare allele of either the APOA5 c.56 G>C, SNP3, APOC3 −1131 T>C or LPL c.27 G>A and carrier represents carrier of the rare allele of either the APOA5 c.56 G>C, SNP3, APOC3 −1131 T>C or LPL c.27 G>A.