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. 2009 Feb 18;17(8):991–998. doi: 10.1038/ejhg.2009.10

Table 1. Notable azathioprine-related fatalities and serious ADRs reported to the UK Medicines Control Agency from 1 July 1963 until 19 May 2006.

Adverse event Reported events Reported fatalities
(A) All causes 1030 110
     
(B) Leading serious adverse events associated with fatalities
 Pancytopenia 55 3
 Thrombocytopenia 32 2
 Leucopenia 24 2
 Bone marrow depression 24 2
 Agranulocytosis 16 2
 Aplastic anemia 14 5
 Sepsis 11 4
 Granulocytopenia 8 1
 Hepatic failure 5 5
 Febrile neutropenia 2 1