Table 2. Stratification analyses of the FASL rs763110 polymorphism on cancer risk.

		CT vs CC			TT vs CC
Variables	Comparisons	OR (95% CI)a	OR (95% CI)b	Phet*	OR (95% CI)a	OR (95% CI)b	Phet*
Total	19	0.82 (0.72–0.95)	0.85 (0.80–0.90)	<0.001	0.80 (0.68–0.95)	0.84 (0.76–0.92)	0.001
Tumor types
Cervical cancer	4	0.87 (0.62–1.22)	0.84 (0.72–0.99)	0.005	0.76 (0.46–1.28)	0.79 (0.58–1.07)	0.074
Breast cancer	3	0.93 (0.75–1.14)	0.92 (0.82–1.04)	0.063	0.82 (0.62–1.07)	0.86 (0.71–1.03)	0.156
Lung cancer	3	0.86 (0.55–1.33)	0.87 (0.79–0.97)	<0.001	0.84 (0.58–1.23)	0.89 (0.76–1.04)	0.012
Other cancers	9	0.74 (0.58–0.94)	0.78 (0.71–0.86)	<0.001	0.79 (0.56–1.12)	0.78 (0.65–0.92)	0.003
Smoking-related cancers	7	0.75 (0.58–0.97)	0.80 (0.74–0.86)	<0.001	0.74 (0.57–0.97)	0.80 (0.71–0.91)	0.002
Estrogen-related cancers	8	0.87 (0.72–1.05)	0.88 (0.80–0.97)	0.002	0.77 (0.60–0.99)	0.82 (0.70–0.96)	0.078
Ethnicities
Asian	10	0.70 (0.59–0.84)	0.68 (0.63–0.74)	<0.001	0.63 (0.51–0.79)	0.62 (0.53–0.73)	0.103
European	9	1.04 (0.96–1.13)	1.04 (0.96–1.12)	0.419	0.98 (0.83–1.14)	0.98 (0.87–1.10)	0.166
Source of controls
Population-based	9	0.77 (0.63–0.95)	0.75 (0.70–0.81)	<0.001	0.72 (0.54–0.95)	0.74 (0.65–0.85)	<0.001
Hospital-based	10	0.93 (0.81–1.07)	0.98 (0.90–1.07)	0.048	0.95 (0.83–1.08)	0.94 (0.83–1.08)	0.481
		TT/CT vs CC (dominant)			TT vs CT/CC (recessive)
		OR (95% CI)a	OR (95% CI)b	Phet*	OR (95% CI)a	OR (95% CI)b	Phet*
Total	19	0.82 (0.71–0.94)	0.84 (0.80–0.89)	<0.001	0.87 (0.77–0.99)	0.88 (0.81–0.96)	0.074
Tumor types
Cervical cancer	4	0.86 (0.60–1.23)	0.83 (0.72–0.97)	0.001	0.83 (0.57–1.20)	0.84 (0.62–1.13)	0.265
Breast cancer	3	0.90 (0.74–1.10)	0.90 (0.80–1.01)	0.055	0.85 (0.69–1.05)	0.87 (0.74–1.04)	0.256
Lung cancer	3	0.85 (0.56–1.31)	0.87 (0.79–0.95)	<0.001	0.90 (0.76–1.08)	0.91 (0.79–1.06)	0.292
Other cancers	9	0.75 (0.59–0.96)	0.78 (0.71–0.86)	<0.001	0.91 (0.68–1.20)	0.86 (0.73–1.02)	0.022
Smoking-related cancers	7	0.74 (0.58–0.95)	0.79 (0.73–0.85)	<0.001	0.83 (0.69–1.01)	0.86 (0.76–0.97)	0.086
Estrogen-related cancers	8	0.85 (0.70–1.03)	0.87 (0.79–0.95)	0.001	0.86 (0.74–1.00)	0.86 (0.74–1.00)	0.448
Ethnicities
Asian	10	0.69 (0.59–0.82)	0.67 (0.62–0.73)	<0.001	0.74 (0.62–0.89)	0.73 (0.63–0.86)	0.287
European	9	1.02 (0.95–1.11)	1.03 (0.95–1.11)	0.372	0.96 (0.85–1.10)	0.96 (0.86–1.07)	0.272
Source of controls
Population-based	9	0.77 (0.62–0.94)	0.74 (0.69–0.80)	<0.001	0.80 (0.65–0.99)	0.82 (0.73–0.93)	0.014
Hospital-based	10	0.93 (0.82–1.06)	0.98 (0.90–1.06)	0.073	0.95 (0.83–1.07)	0.94 (0.83–1.07)	0.722

^aRandom-effects model.

^bFixed-effects model.

^*P-value of Q-test for heterogeneity test.

Smoking-related cancers: lung, bladder, esophageal, head and neck, and pancreatic cancers.

Estrogen-related cancers: breast, cervical, and ovarian cancers.