Table 1. Clinical features of six individuals affected by OODD.
| Clinical feature | IV:3 | V:2 | V:3 | V:5 | V:6 | V:7 |
|---|---|---|---|---|---|---|
| Sex | M | F | M | M | M | M |
| Absence of hair at birth | + | − | − | ? | − | ± |
| Congenital absence of nails | − | − | − | − | − | − |
| Dystrophic fingernails | ± | − | − | − | − | − |
| Dystrophic toe-nails | + | + | + | − | ± | − |
| Erythematous atrophic patches in the face | − | − | ± | − | − | − |
| Palmoplantar keratoderma | − | + | ± | + | + | + |
| Hyperhidrosis | + | + | + | + | + | + |
| Oligodontia | + | + | + | + | + | + |
| Reduced papillae of the tongue | + | + | + | + | + | ± |
| Partial alopecia (male pattern) | − | − | + | − | − | + |
| Sparse eyelashes and/or eyebrows | − | − | − | + | − | − |
| Sparse axillary and/or pubic hair | − | − | + | − | + | − |
| Abnormal hair pattern | − | ± | + | ± | ± | ± |
| Diffuse follicular hyperkeratosis | + | ± | + | + | ± | ± |
| Dry skin | + | + | + | + | + | + |
+, Present; −, absent; ±, subnormal; ?, denote unknown.