. 2009 Jul 8;18(1):88–94. doi: 10.1038/ejhg.2009.119

Table 2. Probability of disease given exposure and genotype statuses according to genetic and environmental model parameters.

	Genotype
Exposure	G− (1–f_G)	G+ (f_G)
E− (1–f_E)	B	B.RR_G
E+ (f_E)	B.RR_E	B.RR_G.RR_E.I

Abbreviations: E+, exposed; E−, unexposed; f_E, proportion of exposed individuals in population; G+, carrier of the predisposing genotype(s); G−, noncarrier of the predisposing genotype(s); f_G, proportion of carriers of the predisposing genotype(s) in population; B, baseline risk; RR_E, exposure relative risk; RR_G, genotypic relative risk; I, multiplicative interaction coefficient for individuals both exposed and carrier of the predisposing genotype.