Table 1. Sociodemographic and clinical characteristics of HCM mutation carriers and a comparison of mutation carriers applying for an insurance without and with experienced problems.
Characteristics | All mutation carriers | Mutation carriers applying for an insurance | P-value | ||||
---|---|---|---|---|---|---|---|
n=228 | Without problems n=27 | With problems n=39 | |||||
n | % | n | % | n | % | ||
Age (mean (SD)) | 49.0 (15.4) | 42.6 (13.8) | 45.3 (11.3) | 0.413 | |||
Male | 112 | 49.1 | 10 | 37.0 | 23 | 59.0 | 0.132 |
Having children | 184 | 80.7 | 18 | 66.7 | 33 | 84.6 | 0.135 |
Partner | 192 | 84.2 | 22 | 81.5 | 34 | 87.2 | 0.729 |
Level of education | |||||||
Low | 71 | 31.1 | 3 | 11.1 | 9 | 23.1 | 0.411 |
Medium | 102 | 44.7 | 12 | 44.4 | 17 | 43.6 | |
High | 55 | 24.1 | 12 | 44.4 | 13 | 33.3 | |
Ethnic background | |||||||
Dutch | 224 | 98.2 | 27 | 100 | 38 | 97.4 | 1.000 |
Other | 4 | 1.8 | 0 | 0 | 1 | 0.6 | |
Physical comorbidity | 101 | 44.3 | 8 | 29.6 | 17 | 43.6 | 0.307 |
Clinical diagnosis of HCM | 135 | 59.2 | 14 | 51.9 | 36 | 92.3 | <0.001 |
Heart complaints | 59 | 25.9 | 9 | 33.3 | 23 | 59.0 | 0.049 |
SCD in familya | |||||||
Yes | 120 | 53.1 | 20 | 74.1 | 21 | 53.8 | 0.058 |
No | 59 | 26.1 | 6 | 22.2 | 8 | 20.5 | |
Does not know | 47 | 20.8 | 1 | 3.7 | 10 | 25.6 | |
Years since DNA test result (mean (SD)) | 3.3 (1.4) | 3.5 (1.0) | 3.9 (1.5) | 0.290 | |||
DNA test in predictive setting | 123 | 53.9 | 14 | 51.9 | 6 | 15.4 | 0.002 |
HCM, hypertrophic cardiomyopathy; SCD, sudden cardiac death. P-values <0.05 are in bold text.
Unknown in two mutation carriers.