Table 1. Summary of the size and position of the tested CNEs (NCBI build 36.1), their homology to chick and the results of the enhancer assay.
Human | CNE-5 | CNE-4 | CNE-3 | CNE-2 |
---|---|---|---|---|
Length | 550 | 181 | 386 | 620 |
Position in the genome | chrX: 318 357–318 906 | chrX: 353 488–353 668 | chrX: 380 279–380 664 | chrX: 436 610–437 229 |
GC content | 57% | 44% | 44% | 46% |
Homology to chick | 72% | 83% | 71% | 76% |
GFP expression in the limb bud | +(18/18) | −(0/13) | +(6/7) | +(5/9) |
GFP expression in the cornea | −(0/7) | −(0/6) | −(0/7) | −(0/4) |
The results are stated as enhancer activity detected (+) or no enhancer activity detected (−). Number of positive cases/total number of cases are given in brackets.