Table 1. Clinical characteristics of the study populations.
| African American | Japanese | |||||
|---|---|---|---|---|---|---|
| Panel A | Total | Asthma | Controls | Total | Asthma | Controls |
| Subjects (n) | 935 | 464 | 471 | 925 | 468 | 457 |
| Males, n (%) | 406 (43.4%) | 211 (45.5%) | 195 (41.4%) | 515 (55.7%) | 220 (47.0%) | 295 (64.6%) |
| Age; mean (SD) | 29.55 (18.10) | 23.78 (17.85) | 35.23 (16.51) | 42.4 (15.7) | 45.9 (16.8) | 38.8 (13.6) |
| Total IgE; meana (95% CI) | 213.7 (191.5–238.4) | 315.6 (270.4–368.3) | 143.3 (123.8–165.8) | 132.6 (119.6–147.0) | 242.7 (211.0–279.1) | 71.8 (63.1–81.7) |
| Atopy, n (%) | 641 (75.2%) | 369 (85.2%) | 272 (64.9%) | 587 (63.5%) | 339 (72.4) | 248 (54.3) |
| Brazilian families | Caucasian | |||||
| Panel B | Total | Wheeze | Control | Total | EE | Control |
| Subjects (n) | 822 | 244 | 550 | 298 | 166 | 132 |
| Males (%) | 363 (44.2%) | 114 (46.7%) | 233 (42.4%) | 166 (55.7%) | 102 (61.4%) | 64 (48.5%) |
| Age; mean (SD) | 26.9 (18.75) | 26.6 (18.87) | 27.0 (18.70) | — | — | — |
| Total IgE; meana (95% CI) | 2505.6 (2296.1–2734.3) | 2631.2 (2292.9–3019.5) | 2450.9 (2194.3–2737.4) | — | — | — |
a
Geometric mean serum levels of total IgE.