Table 2. Conditional logistic regression analyses for IL2RA polymorphisms with single-point allelic P<0.05 in the combined cohorts from Madrid and Andalucía (1247 MS cases and 1491controls).
| (a) Add locus to rs2104286 | (b) Add rs2104286 to locus | ||||||
|---|---|---|---|---|---|---|---|
| Locus | OR | (95% CI) | P-value | OR | (95% CI) | P-value | |
| rs41295061 | C | 1.00 | (0.76–1.31) | 0.98 | 0.74 | (0.63–0.87) | 0.0003 |
| rs35285258 | T | 1.14 | (1.01–1.29) | 0.03 | 0.80 | (0.69–0.93) | 0.0038 |
Regression analyses (a) adding rs41295061 and rs35285258 to rs2104286 and (b) adding rs2104286 to rs41295061 and rs35285258. Results for a model assuming multiplicative effects.