Table 3. Logistic regression of test status of non-parent relatives on potential predictors of uptake of carrier testing.
| Proportion tested (%) | Unadjusted analysis OR; 95% CI; P-value | Multivariable analysis AOR; 95% CI; P-value | |
|---|---|---|---|
| Gender of relativea | |||
| Female | 14.5 | 1.64; 1.20–2.25; 0.002 | 1.61; 1.11–2.33; 0.01 |
| Male | 9.45 | Reference group | Reference group |
| Maternal or paternal relatives | |||
| Paternal | 12.1 | 1.19; 0.66–2.13; 0.55 | 1.14; 0.69–1.91; 0.60 |
| Maternal | 10.9 | Reference group | Reference group |
| Carrier risk based on relationship to child with CF | |||
| 1 in 2 | 31.8 | 5.56; 2.47–12.52; <0.001 | 5.17; 2.38–11.24; <0.001 |
| 1 in 4 | 6.6 | Reference group | Reference group |
| 1 in 8 | 1.0 | —b | —b |
Abbreviations: AOR, adjusted odds ratio; CI, confidence interval; OR, odds ratio.
N=716.
a
There were 37 non-parent relatives for whom gender could not be confirmed by the parents in the interview and these have been excluded from this analysis of the gender variable.
b
The odds ratio could not be calculated due to the very small number of participants in this group.